The aesthetic objections to live-saving Indie PEN
The medical reformers controlling the (glacial) pace of the mass introduction of penicillin (from 1928 to 1944) viewed the idea of saving the lives of dying patients with crude (Indie PEN) penicillin with the same sort of distaste they held towards mothers who still breastfed.
They all wanted penicillin that was first of all was pure and stable.
Some further wanted to wait until it was chemically synthesized (patentable) and many others wanted to keep it secret and limit it only for Allied wounded soldiers while the war raged.
And if countless patients died needlessly while they polished the turd - so be it .